Curated luxury hotels in Santo Spirito

Search
Add dates
Add dates
1 room, 2 guests
Compare deals on Booking.com

Trusted by over 100,000 travellers every year

back
close
Add dates
Add dates
Room 1

Adults

18+ years
2

Children

0-17
0
Add another room
usp icon

Exclusive member prices

Unlock exclusive member discounts at hundreds of top hotels.

usp icon

The biggest range

Thousands of luxury hotels for you to choose from but all curated for you.

usp icon

The best price

We compare deals and bring you the best price with our price promise.

usp icon

Free cancellation & pay later

A range of fully refundable and pay on arrival luxury and boutique hotels.

Clear filters

Santo Spirito

Recommended

See the latest prices and deals by choosing your dates

These properties may not be in the centre of Santo Spirito, but are nearby and match your search.
Primary image
Ruby Bea Hotel Florence
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in San Lorenzo, Florence · 1.72 mi from centre

9.2

 

104 reviews

Breakfast available

With a stay at Ruby Bea Hotel Florence, you'll be centrally located in Florence, just a 3-minute walk from Historic Centre of Florence and 13 minutes by foot from Gallery of the Academy of Florence. This hotel is 0.8 mi (1.2 km) from Fortezza da Basso and 1.7 mi (2.8 km) from Cathedral of Santa Maria del Fiore.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Arte' Boutique Hotel
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in San Lorenzo, Florence · 1.14 mi from centre

9.6

 

248 reviews

Breakfast available

With a stay at Arte' Boutique Hotel, you'll be centrally located in Florence, steps from Historic Centre of Florence and 5 minutes by foot from Cathedral of Santa Maria del Fiore. This hotel is 0.5 mi (0.8 km) from Piazza di Santa Maria Novella and 0.6 mi (0.9 km) from Uffizi Gallery.

Compare price on Booking.com
Compare price on Booking.com
Flom Boutique Hotel
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in San Lorenzo, Florence · 1.11 mi from centre

9.1

 

674 reviews

Situated in the heart of Florence, within the ex-convent of the Church of San Barnaba, Flom hotel offers its guests fully renovated surroundings.
All our rooms are furnished with artisanal furniture and offer a smart tv with satellite channels, air-conditioning, minibar, safe, kettle, hairdryer and ensuite bathroom complete with guest toiletries from the historical Florentine Santissima Annunziata Pharmacy.
The hotel serves a continental buffet breakfast every morning.
The reception is open 24 hours a day and our staff will be happy to provide any information or suggestions during your stay in Florence.
Flom hotel is located 600m from Florence SMN train station, 700 m from the Cathedral, 500m from the convention centre – Fortezza da Basso - and 200 m from the central market.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Borghese Palace Art Hotel
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in Duomo, Florence · 1.13 mi from centre

8.4

 

678 reviews

Breakfast available

With a stay at Borghese Palace Art Hotel, you'll be centrally located in Florence, steps from Historic Centre of Florence and 6 minutes by foot from Uffizi Gallery. This boutique hotel is 0.3 mi (0.5 km) from Cathedral of Santa Maria del Fiore and 0.7 mi (1.1 km) from Piazza di Santa Maria Novella.

Compare price on Booking.com
Compare price on Booking.com
Primary image
The Social Hub Florence Lavagnini
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in San Lorenzo, Florence · 1.30 mi from centre

8.8

 

966 reviews

Breakfast available

Centrally located in Florence, The Social Hub Florence Lavagnini is within a 15-minute walk of Gallery of the Academy of Florence and Florence Baptistery. This hotel is 1.5 mi (2.4 km) from Piazza della Signoria and 1.8 mi (2.9 km) from Bargello.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Hilton Garden Inn Florence Novoli
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in Florence · 1.84 mi from centre

8.6

 

779 reviews

Breakfast available

Located in Florence, Hilton Garden Inn Florence Novoli is a 5-minute drive from Basilica of Santa Maria Novella and 6 minutes from Pitti Palace. This hotel is 2.6 mi (4.2 km) from Piazza della Signoria and 2.7 mi (4.4 km) from Gallery of the Academy of Florence.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Hotel Balestri
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in Santa Croce, Florence · 1.04 mi from centre

9.0

 

909 reviews

With a stay at Hotel Balestri, you'll be centrally located in Florence, steps from Historic Centre of Florence and 4 minutes by foot from Uffizi Gallery. This hotel is 0.5 mi (0.9 km) from Cathedral of Santa Maria del Fiore and 0.7 mi (1.2 km) from Piazza di Santa Maria Novella.

Compare price on Booking.com
Compare price on Booking.com
Reception
Glimpse Hotel
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in Duomo, Florence · 1.20 mi from centre

9.6

 

62 reviews

Breakfast available

With a stay at Glimpse Hotel, you'll be centrally located in Florence, steps from Historic Centre of Florence and 3 minutes by foot from Cathedral of Santa Maria del Fiore. This hotel is 0.5 mi (0.9 km) from Piazza di Santa Maria Novella and 0.6 mi (0.9 km) from Uffizi Gallery.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Globus Urban Hotel
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in Duomo, Florence · 0.97 mi from centre

9.2

 

996 reviews

With a stay at Globus Urban Hotel, you'll be centrally located in Florence, steps from Historic Centre of Florence and within a 10-minute walk of Piazza di Santa Maria Novella. This hotel is 0.6 mi (1 km) from Piazza della Signoria and 1.1 mi (1.7 km) from Pitti Palace.

Compare price on Booking.com
Compare price on Booking.com
Primary image
De La Pace, Sure Hotel Collection by Best Western
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in San Lorenzo, Florence · 1.58 mi from centre

7.6

 

342 reviews

With a stay at De La Pace, Sure Hotel Collection by Best Western, you'll be centrally located in Florence, steps from Historic Centre of Florence and 13 minutes by foot from Cathedral of Santa Maria del Fiore. This hotel is 0.4 mi (0.6 km) from Gallery of the Academy of Florence and 0.7 mi (1.1 km) from Piazza del Duomo.

Compare price on Booking.com
Compare price on Booking.com
Primary image
The Market Urban Hotel
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in Santa Maria Novella, Florence · 0.97 mi from centre

9.4

 

952 reviews

Breakfast available

With a stay at The Market Urban Hotel, you'll be centrally located in Florence, steps from Historic Centre of Florence and 6 minutes by foot from Piazza di Santa Maria Novella. This hotel is 0.4 mi (0.7 km) from Cathedral of Santa Maria del Fiore and 0.7 mi (1.1 km) from Uffizi Gallery.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Solo Experience Hotel
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in Duomo, Florence · 1.01 mi from centre

9.4

 

606 reviews

Breakfast available

With a stay at Solo Experience Hotel, you'll be centrally located in Florence, steps from Historic Centre of Florence and 5 minutes by foot from Cathedral of Santa Maria del Fiore. This hotel is 0.3 mi (0.5 km) from Piazza di Santa Maria Novella and 0.6 mi (1 km) from Uffizi Gallery.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Hotel Rapallo
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in San Lorenzo, Florence · 1.31 mi from centre

9.4

 

980 reviews

Breakfast available

With a stay at Hotel Rapallo, you'll be centrally located in Florence, steps from Historic Centre of Florence and 12 minutes by foot from Piazza di Santa Maria Novella. This hotel is 0.7 mi (1.2 km) from Cathedral of Santa Maria del Fiore and 0.3 mi (0.5 km) from Central Market.

Compare price on Booking.com
Compare price on Booking.com
Primary image
FH55 Hotel Calzaiuoli
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in San Giovanni, Florence · 0.95 mi from centre

8.8

 

948 reviews

Breakfast available

A stay at FH55 Hotel Calzaiuoli places you in the heart of Florence, steps from Historic Centre of Florence and Piazza della Signoria. This hotel is 0.2 mi (0.3 km) from Cathedral of Santa Maria del Fiore and 0.2 mi (0.4 km) from Uffizi Gallery.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Hotel Botticelli
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in San Lorenzo, Florence · 1.10 mi from centre

8.6

 

820 reviews

Breakfast available

A stay at Hotel Botticelli places you in the heart of Florence, steps from Historic Centre of Florence and Central Market. This hotel is 0.3 mi (0.5 km) from Cathedral of Santa Maria del Fiore and 0.4 mi (0.7 km) from Piazza di Santa Maria Novella.

Compare price on Booking.com
Compare price on Booking.com
Primary image
San Firenze Suites & Spa
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in San Giovanni, Florence · 1.03 mi from centre

9.6

 

978 reviews

Breakfast available

With a stay at San Firenze Suites & Spa, you'll be centrally located in Florence, steps from Piazza della Signoria and within a 5-minute walk of Palazzo Vecchio. This spa hotel is 0.5 mi (0.9 km) from Cathedral of Santa Maria del Fiore and 0.5 mi (0.9 km) from Piazza del Duomo.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Hotel Leonardo Da Vinci
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in Porta al Prato, Florence · 0.96 mi from centre

9.0

 

618 reviews

Breakfast available

With a stay at Hotel Leonardo Da Vinci, you'll be centrally located in Florence, within a 10-minute walk of Fortezza da Basso and Palazzo dei Congressi. This hotel is 1.1 mi (1.8 km) from Central Market and 1.6 mi (2.5 km) from Piazza di Santa Maria Novella.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Relais Uffizi, Tailor made Hotel
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in San Giovanni, Florence · 0.91 mi from centre

9.2

 

73 reviews

Breakfast available

With a stay at Relais Uffizi, Tailor made Hotel, you'll be centrally located in Florence, steps from Piazza della Signoria and Uffizi Gallery. This hotel is 0.5 mi (0.8 km) from Arno River and 0.6 mi (0.9 km) from Ponte Vecchio.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Eurostars Florence Boutique
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in Santa Croce, Florence · 1.55 mi from centre

8.4

 

448 reviews

Breakfast available

With a stay at Eurostars Florence Boutique, you'll be centrally located in Florence, within a 10-minute walk of Church of Sant'Ambrogio and Basilica of Santa Croce. This boutique hotel is 0.8 mi (1.3 km) from Teatro Verdi.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Room Mate Luca
Full StarFull StarFull StarFull Star
This star rating is provided to My Luxury Hotel by the property. It is usually determined by an official hotel rating organisation or another third party.

Hotel in San Lorenzo, Florence · 1.24 mi from centre

9.2

 

979 reviews

Breakfast available

With a stay at Room Mate Luca, you'll be centrally located in Florence, steps from Historic Centre of Florence and 10 minutes by foot from Cathedral of Santa Maria del Fiore. This hotel is 0.6 mi (1 km) from Piazza di Santa Maria Novella and 0.2 mi (0.4 km) from Gallery of the Academy of Florence.

Compare price on Booking.com
Compare price on Booking.com
tripadvisor