Curated luxury hotels in Santo Spirito

Search
Add dates
Add dates
1 room, 2 guests
Compare deals on Booking.com

Trusted by over 100,000 travellers every year

back
close
Add dates
Add dates
room 1

Adults

18+
2

Child

0-17
0
Add another room
usp icon

Exclusive member prices

Unlock exclusive member discounts at hundreds of top hotels.

usp icon

The biggest range

Thousands of luxury hotels for you to choose from but all curated for you.

usp icon

The best price

We compare deals and bring you the best price with our price promise.

usp icon

Free cancellation & pay later

A range of fully refundable and pay on arrival luxury and boutique hotels.

Clear filters

Santo Spirito

Recommended
Sort by

See the latest prices and deals by choosing your dates

These properties may not be in the centre of Santo Spirito, but are nearby and match your search.
Primary image
The Social Hub Florence Lavagnini
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in San Lorenzo, Florence · 2.09 km from centre

8.8

 

1,009 reviews

Breakfast available

Centrally located in Florence, The Social Hub Florence Lavagnini is within a 15-minute walk of Gallery of the Academy of Florence and Florence Baptistery. This hotel is 1.5 mi (2.4 km) from Piazza della Signoria and 1.8 mi (2.9 km) from Bargello.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Starhotels Tuscany
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in Florence · 2.90 km from centre

8.8

 

979 reviews

Breakfast available

When you stay at Starhotels Tuscany in Florence, you'll be in the business district, within a 5-minute drive of Piazza di Santa Maria Novella and Fortezza da Basso. This family-friendly hotel is 3.5 mi (5.6 km) from Cathedral of Santa Maria del Fiore and 4.6 mi (7.5 km) from Uffizi Gallery.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Relais Uffizi, Tailor made Hotel
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in San Giovanni, Florence · 1.46 km from centre

9.2

 

88 reviews

Breakfast available

With a stay at Relais Uffizi, Tailor made Hotel, you'll be centrally located in Florence, steps from Piazza della Signoria and Uffizi Gallery. This hotel is 0.5 mi (0.8 km) from Arno River and 0.6 mi (0.9 km) from Ponte Vecchio.

Compare price on Booking.com
Compare price on Booking.com
Reception
Art Atelier
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in Duomo, Florence · 1.48 km from centre

9.0

 

858 reviews

Breakfast available

With a stay at Art Atelier, you'll be centrally located in Florence, within a 5-minute walk of Piazza di Santa Maria Novella and Basilica of Santa Maria Novella. This hotel is 0.3 mi (0.5 km) from Cathedral of Santa Maria del Fiore and 0.2 mi (0.3 km) from Central Market.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Aurum Uffizi
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in Santa Croce, Florence · 1.63 km from centre

7.8

 

1,000 reviews

Breakfast available

A stay at Aurum Uffizi places you in the heart of Florence, steps from Uffizi Gallery and Palazzo Vecchio. This hotel is 0.6 mi (1 km) from Piazza di Santa Maria Novella and 0.2 mi (0.3 km) from Piazza della Signoria.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Villa Royal
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in San Lorenzo, Florence · 2.22 km from centre

8.8

 

313 reviews

Breakfast available

A stay at Villa Royal places you in the heart of Florence, within a 15-minute walk of Piazza di Santa Maria Novella and Cathedral of Santa Maria del Fiore. This hotel is 0.4 mi (0.6 km) from Central Market and 0.5 mi (0.8 km) from Fortezza da Basso.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Eurostars Florence Boutique
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in Santa Croce, Florence · 2.49 km from centre

8.4

 

453 reviews

Breakfast available

With a stay at Eurostars Florence Boutique, you'll be centrally located in Florence, within a 10-minute walk of Church of Sant'Ambrogio and Basilica of Santa Croce. This boutique hotel is 0.8 mi (1.3 km) from Teatro Verdi.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Allegroitalia San Gallo Firenze
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in San Lorenzo, Florence · 2.75 km from centre

8.8

 

972 reviews

With a stay at Allegroitalia San Gallo Firenze, you'll be centrally located in Florence, within a 5-minute drive of Piazza di Santa Maria Novella and Fortezza da Basso. This hotel is 2.2 mi (3.5 km) from Cathedral of Santa Maria del Fiore and 2.8 mi (4.5 km) from Uffizi Gallery.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Donati Luxury Tower Suites
Full StarFull StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in San Giovanni, Florence · 1.59 km from centre

9.6

 

30 reviews

With a stay at Donati Luxury Tower Suites, you'll be centrally located in Florence, steps from Cathedral of Santa Maria del Fiore and 8 minutes by foot from Piazza di Santa Maria Novella. This luxury hotel is 0.2 mi (0.2 km) from Piazza della Signoria and 0.2 mi (0.4 km) from Piazza del Duomo.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Room Mate Luca, Florence
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in San Lorenzo, Florence · 2.00 km from centre

9.2

 

985 reviews

Breakfast available

With a stay at Room Mate Luca, Florence, you'll be centrally located in Florence, just a 5-minute walk from Central Market and 10 minutes by foot from Cathedral of Santa Maria del Fiore. This hotel is 0.5 mi (0.9 km) from Piazza di Santa Maria Novella and 0.4 mi (0.7 km) from Fortezza da Basso.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Mercure Firenze Centro
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in Santa Maria Novella, Florence · 1.51 km from centre

8.8

 

772 reviews

Breakfast available

A stay at Mercure Firenze Centro places you in the heart of Florence, within a 5-minute walk of Basilica of Santa Maria Novella and Central Market. This hotel is 0.3 mi (0.5 km) from Medici Chapels and 0.4 mi (0.6 km) from San Lorenzo Church.

Compare price on Booking.com
Compare price on Booking.com
Primary image
The Social Hub Florence Belfiore
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in Porta al Prato, Florence · 1.64 km from centre

9.4

 

52 reviews

Breakfast available

Located in Florence (Santa Maria Novella), The Social Hub Florence Belfiore is within a 15-minute walk of Fortezza da Basso and Basilica of Santa Maria Novella. This hotel is 0.8 mi (1.3 km) from Piazza di Santa Maria Novella and 2.2 mi (3.6 km) from Cathedral of Santa Maria del Fiore.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Aurum Firenze
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in Santa Maria Novella, Florence · 1.51 km from centre

7.6

 

1,000 reviews

Breakfast available

With a stay at Aurum Firenze, you'll be centrally located in Florence, within a 5-minute walk of Piazza di Santa Maria Novella and Basilica of Santa Maria Novella. This hotel is 0.4 mi (0.7 km) from Cathedral of Santa Maria del Fiore and 0.2 mi (0.3 km) from Central Market.

Compare price on Booking.com
Compare price on Booking.com
Primary image
Residence Select Executive
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in Porta al Prato, Florence · 1.77 km from centre

7.4

 

27 reviews

With a stay at Residence Select Executive in Florence (Santa Maria Novella), you'll be within a 5-minute drive of Piazza di Santa Maria Novella and Fortezza da Basso. This hotel is 2.6 mi (4.3 km) from Cathedral of Santa Maria del Fiore and 3.8 mi (6.1 km) from Uffizi Gallery.

Compare price on Booking.com
Compare price on Booking.com
Il Nespolo by Monteverdi apartments
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in Florence · 2.95 km from centre

9.0

 

43 reviews

Located in Florence, near Accademia Gallery, Fortezza da Basso - Convention Center and Piazza del Duomo di Firenze, Il Nespolo by Monteverdi apartments features a garden. Among the facilities at this property are private check-in and check-out and bicycle parking, along with free WiFi throughout the property. The property is non-smoking and is set less than 1 km from San Marco Church in Florence.

This apartment is fitted with 1 bedroom, a flat-screen TV, a dining area, a fully equipped kitchen with a fridge, and a living room. Guests can take in the views of the garden from the terrace, which also has outdoor furniture.

Cathedral of Santa Maria del Fiore is 1.7 km from the apartment, while Piazza della Signoria is 3.2 km away. The nearest airport is Florence Airport, 9 km from Il Nespolo by Monteverdi apartments.

Compare price on Booking.com
Compare price on Booking.com
Elegante casa ai piedi di Piazzale Michelangelo
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in Florence · 2.06 km from centre

9.3

 

40 reviews

A recently renovated property, Elegante casa ai piedi di Piazzale Michelangelo is located in Florence near Ponte Vecchio, Uffizi Gallery and Palazzo Vecchio. Among the facilities at this property are a concierge service and private check-in and check-out, along with free WiFi throughout the property. The property is non-smoking and is situated 1.2 km from Piazza della Signoria.

The 1-bedroom apartment is equipped with a living room with a flat-screen TV with streaming services, a fully equipped kitchen with a dishwasher and an oven, and 1 bathroom with a hair dryer. Towels and bed linen are provided in the apartment.

Popular points of interest near the apartment include Cathedral of Santa Maria del Fiore, Piazza del Duomo di Firenze and Piazzale Michelangelo. The nearest airport is Florence, 12 km from Elegante casa ai piedi di Piazzale Michelangelo, and the property offers a paid airport shuttle service.

Compare price on Booking.com
Compare price on Booking.com
Apt. Perla - Pauline Suites, Palazzo Borghese
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in Florence · 1.80 km from centre

9.2

 

33 reviews

In the heart of Florence, set within a short distance of Piazza della Signoria and Cathedral of Santa Maria del Fiore, Apt. Perla - Pauline Suites, Palazzo Borghese offers free WiFi, air conditioning and household amenities such as a fridge and kettle. It is situated 600 metres from Uffizi Gallery and offers a lift. The property is non-smoking and is located 500 metres from Piazza del Duomo di Firenze.

The apartment features 1 bedroom, a TV with streaming services, a fully equipped kitchenette with an oven and a microwave, a washing machine, and 1 bathroom with a bidet. Towels and bed linen are featured in the apartment. The property offers city views.

Popular points of interest near the apartment include Accademia Gallery, Palazzo Vecchio and Ponte Vecchio. The nearest airport is Florence Airport, 11 km from Apt. Perla - Pauline Suites, Palazzo Borghese.

Compare price on Booking.com
Compare price on Booking.com
Moonlight
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in Florence · 1.66 km from centre

9.5

 

6 reviews

Located in Florence, 1.4 km from Fortezza da Basso - Convention Center and 1.8 km from Strozzi Palace, Moonlight offers air conditioning. The property is around 3.6 km from Piazza del Duomo di Firenze, 4.1 km from Piazza della Signoria and 4.1 km from Cathedral of Santa Maria del Fiore. Free WiFi is available throughout the property and Santa Maria Novella is 1.6 km away.

This apartment comes with 1 bedroom, a kitchen with a dishwasher and an oven, a flat-screen TV, a seating area and 1 bathroom equipped with a bidet. Towels and bed linen are featured in the apartment. For added privacy, the accommodation features a private entrance.

Accademia Gallery is 4.4 km from the apartment, while San Marco Church in Florence is 4.6 km away. The nearest airport is Florence Airport, 8 km from Moonlight.

Compare price on Booking.com
Compare price on Booking.com
Hotel Art Atelier - Place of Charme
Full StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in Duomo, Florence · 1.50 km from centre

9.0

 

1,035 reviews

Breakfast available

Hotel Art Atelier - Place of Charme is a 4-star boutique property 100 metres from Florence's Medici Chapels. All rooms offer an LCD TV and free Wi-Fi.

Rooms at the Art Atelier feature stuccoed ceilings, parquet floors or carpeted floors and a marble bathroom. Each has a tea/coffee maker.

Art Atelier Hotel is a 5-minute walk from the Cathedral.

Compare price on Booking.com
Compare price on Booking.com
Hotel Bernini Palace
Full StarFull StarFull StarFull StarFull Star
[missing: cards.star_rating_info]

Hotel in San Giovanni, Florence · 1.66 km from centre

9.0

 

903 reviews

Breakfast available

Set in a 15th-century building, Hotel Bernini Palace is a 5-minute walk from Florence Cathedral and Ponte Vecchio. It features antique furniture and Murano-glass chandeliers.

Some rooms are decorated in a classic style. Others boast Renaissance Florence décor with period tapestry and canopy beds. They all come with a satellite flat-screen TV, air conditioning and a minibar. Free Wi-Fi is available throughout the hotel.

Guests can enjoy the panoramic views from the terrace, furnished with tables and chairs. The stylish La Chiostrina Restaurant serves national and international dishes. The lounge bar makes excellent cocktails and a buffet breakfast is provided daily.

The lobby at Bernini Palace Hotel is decorated with a mix of Italian and Moroccan styles.

Compare price on Booking.com
Compare price on Booking.com
tripadvisor